It appears that these other factors often have a greater impact on women's sexual functioning than their menopausal status. Their results suggested that "genes predisposing to homosexuality may confer a mating advantage in heterosexuals, which could help explain the evolution and maintenance of homosexuality in the population". However, the INAH3 group appeared to be twice as big in the heterosexual male group as in the gay male group; the difference was highly significant, and remained significant when only the six AIDS patients were included in the heterosexual group. It is therefore seen as important always to understand the "context of women's lives" when studying their sexuality. While young women may become sexually aroused quite easily, and reach orgasm relatively quickly with the right stimulation in the right circumstances, there are physiological and psychological changes to women's sexual arousal and responses as they age.
The display of secondary sex characteristics in humans such as a penis-like enlarged clitoris in females during arousal and gynecomastia in males are thought to have once been objects of mate selection in human evolution because of the persistence of the phenomenon of these features invoking sexual arousal for potential mates in cross-cultural studies. Those mice who retained the gene fucose mutarotase FucM were attracted to male mice. It can be as long as a few hours or days in mid-life and older men. In some cases though, it appears that this switching off can occur in a non-random fashion. The research consisted of 1, homosexual men and 1, heterosexual men. Some researchers state that solid scientific support for this is lacking. Gringas and Chen describe a number of mechanisms which can lead to differences between monozygotic twins , the most relevant here being chorionicity and amniocity. Repeated or prolonged stimulation without orgasm and ejaculation can lead to discomfort in the testes corresponding to the slang term " blue balls " . Once erect, his penis may gain enough stimulation from contact with the inside of his clothing to maintain and encourage it for some time. Hofman reported a difference in the size of the suprachiasmatic nucleus between homosexual and heterosexual men. There are a variety of methods used to assess genital sexual arousal in women. There is no 'cure' for homosexuality because it is not a disease. As the testicles continue to rise, a feeling of warmth may develop around them and the perineum. In older women, decreased pelvic muscle tone may mean that it takes longer for arousal to lead to orgasm, may diminish the intensity of orgasms, and then cause more rapid resolution. There may be a difference in women's ability to perceive internal versus external genital engorgement subjectively, as measured by vaginal photoplethysmography VPG and thermography respectively. In , they released Human Sexual Response, detailing four stages of physiological changes in humans during sexual stimulation: Although the exact function of the oSDN is not fully known, its volume, length, and cell number seem to correlate with sexual orientation, and a dimorphism in its volume and of cells could bias the processing cues involved in partner selection. Because of their temperament, which is influenced by biological variables such as genetic factors, some children will be attracted to activities that are commonly enjoyed by other children of the same gender. Experts in the evolution of sex such as John Maynard Smith advocate for the idea that the exchange of sexual favors helps congeal and localize the assortment of alleles in isolated population and therefore is potentially a very strong force in evolution. The use of all adult twins in Sweden was designed to address the criticism of volunteer studies, in which a potential bias towards participation by gay twins may influence the results; Biometric modeling revealed that, in men, genetic effects explained. Psychological sexual arousal also has an effect on physiological mechanisms; Goldey and van Anders  showed that sexual cognitions impact hormone levels in women, such that sexual thoughts result in a rapid increase in testosterone in women who were not using hormonal contraception. Having said this, it is more likely that oSDN morphology and homosexuality may be programmed through an androgen receptor that does not involve aromatisation. However, it is unclear whether higher levels of testosterone cause increased arousal and in turn multiple partners or whether sexual activity with multiple partners cause the increase in testosterone. None of similar states of physiological deficiency responsible for the periodical appearance of sexual arousal has been revealed in human sexuality. The results for INAH3 weight were similar to those for INAH3 size; that is, the INAH3 weight for the heterosexual male brains was significantly larger than for the heterosexual female brains, while the results for the gay male group were between those of the other two groups but not quite significantly different from either. The degree to which genital and subjective sexual response correspond is termed concordance.
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